Patient Zero: Plague game

Contains adsIn-app purchases
3.7
4.9K reviews
500K+
Downloads
Content rating
PEGI 12
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About this game

"Patient Zero" is a terrifyingly realistic virus simulator that combines strategic gameplay with a true-to-life global crisis. This is not just another virus game—it's a fully immersive pathogen game where every decision can alter the fate of humanity.

Your virus infection has just begun with "Patient Zero." Now it's your mission to develop a deadly plague and adapt against everything humanity throws at you. This is the ultimate test of survival, cunning, and biology in one of the most intense pandemic games ever made.

Features:
● Hyper-realistic, highly detailed world—experience the depth of a true virus simulation
● Flash controls and intuitive interface to guide you through global domination
● 15 unique types of diseases—each one mutates differently in this complex disease game
● Every country on Earth is available for infection—from major cities to remote islands
● Hundreds of traits to evolve, thousands of world events to respond to
● Built-in tutorials and help system for new players of biology games or infecting games

Will you save the world or watch it fall? Become the ultimate bio-strategist in this pandemic plague game. Whether you’re stopping the outbreak or accelerating the virus infection, the fate of the planet is in your hands.

If you love virus infection games, pandemic simulations, or strategic infecting games, this is the virus game you’ve been waiting for. Adapt. Survive. Infect.

Download Patient Zero now – the most addictive and realistic pandemic and disease game experience on mobile!
Updated on
Aug 18, 2025

Data safety

Safety starts with understanding how developers collect and share your data. Data privacy and security practices may vary based on your use, region, and age. The developer provided this information and may update it over time.
This app may share these data types with third parties
Location, Personal info and 2 others
No data collected
Learn more about how developers declare collection
Data isn’t encrypted
Data can’t be deleted

Ratings and reviews

3.6
4.6K reviews
J Cruickshank
August 30, 2025
The game is fun basically a clone of pandemic. there are ad's but they are short. in the beginning there aren't as many ad's but once you get a bit into the first level the ad's become very aggressive (one ad every 36 seconds). I'm sure you can purchase to remove ads but unfortunately I wasn't able to see how much it was due to battling ads every time I switched any tab. again it is a fun game so if you don't mind watching ad's I recommend the game. 3/5
14 people found this review helpful
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Levias Wolfe
August 10, 2025
I have completed the bacteria strain four times and it will not let you progress to the next pathogen, as others have said. I also have experienced the bug of speeding up immediately shutting off. You have to fully close the game for it to start working again. It is a pretty decent game, but these bugs need to be fixed. I would not make any purchases.
62 people found this review helpful
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Kody Conklin
July 22, 2025
Was fun at first but as some others have said the second pathogen is impossible to get past. You'll get near 4% with almost every mutation and it won't progress. And what's the point in fighting the cure reaserch when you cant fully stop it. You can have the bar at zero but it will just keep going. Either the game is broken and needs to be fixed or its a straight scam and needs to be taken down.
109 people found this review helpful
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What’s new

A new pathogen has been added